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Synthetic biological circuits are an application of synthetic biology where biological parts inside a cell are designed to perform logical functions mimicking those observed in electronic circuits. Typically, these circuits are categorized as either genetic circuits, RNA circuits, or protein circuits, depending on the types of biomolecule that ...
The Dictionary of Protein Secondary Structure, in short DSSP, is commonly used to describe the protein secondary structure with single letter codes. The secondary structure is assigned based on hydrogen bonding patterns as those initially proposed by Pauling et al. in 1951 (before any protein structure had ever been experimentally determined ...
Circuit breaker design pattern. Circuit breaker is a design pattern used in software development. It is used to detect failures and encapsulates the logic of preventing a failure from constantly recurring, during maintenance, temporary external system failure or unexpected system difficulties. Circuit breaker pattern prevents cascading failures ...
Low complexity regions ( LCRs) in protein sequences, also defined in some contexts as compositionally biased regions ( CBRs ), are regions in protein sequences that differ from the composition and complexity of most proteins that is normally associated with globular structure. [1] [2] LCRs have different properties from normal regions regarding ...
Synthetic biology ( SynBio) is a multidisciplinary field of science that focuses on living systems and organisms, and it applies engineering principles to develop new biological parts, devices, and systems or to redesign existing systems found in nature. [ 1]
Modelling biological systems is a significant task of systems biology and mathematical biology. [a] Computational systems biology [b] [1] aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems. It involves the use of computer simulations of ...
Starting in 1990, by 1999, chromosome 22 became the first human chromosome to be completely sequenced. Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. [ 1] An intersection of computer science, biology, and big data, the field also ...
Systems biology is the computational and mathematical analysis and modeling of complex biological systems. It is a biology -based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach ( holism instead of the more traditional reductionism) to biological research. [ 1 ...