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Alteplase, sold under the brand name Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter. [5]
Tissue-type plasminogen activator. Tissue-type plasminogen activator, short name tPA, is a protein that facilitates the breakdown of blood clots. It acts as an enzyme to convert plasminogen into its active form plasmin, the major enzyme responsible for clot breakdown. It is a serine protease ( EC 3.4.21.68) found on endothelial cells lining the ...
Third-party administrator. In the United States, a third-party administrator ( TPA) is an organization that processes insurance claims or certain aspects of employee benefit plans for a separate entity. [ 1] It is also a term used to define organizations within the insurance industry which administer other services such as underwriting and ...
Tennessee : MEM / KMEM Memphis International. Texas : DAL / KDAL Dallas Love Field (lies within the class B surface area of DFW) DFW / KDFW Dallas/Fort Worth International. HOU / KHOU Houston–Hobby (class B secondary airport) IAH / KIAH Houston–George Bush Intercontinental. Utah : SLC / KSLC Salt Lake City International.
Plasminogen activators are serine proteases that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen. Plasmin is an important factor in fibrinolysis, the breakdown of fibrin polymers formed during blood clotting. There are two main plasminogen activators: urokinase (uPA) and tissue plasminogen activator ...
t. e. The Competition and Consumer Act 2010 ( CCA) [ 1] is an Act of the Parliament of Australia. Prior to 1 January 2011, it was known as the Trade Practices Act 1974 ( TPA ). [ 2] The Act is the legislative vehicle for competition law in Australia, and seeks to promote competition, fair trading as well as providing protection for consumers.
Tenecteplase. Tenecteplase, sold under the trade names TNKase, Metalyse and Elaxim, is an enzyme used as a thrombolytic drug . Tenecteplase is a tissue plasminogen activator (tPA) produced by recombinant DNA technology using an established mammalian cell line ( Chinese hamster ovary cells ). Tenecteplase is a 527 amino acid glycoprotein ...
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