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Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [ 10][ 12] is the S (+) enantiomer of ketamine. [ 5][ 13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression. Esketamine is the active enantiomer of ketamine in terms ...
Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine, the drug, as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]
Janssen Pharmaceuticals was the first Western pharmaceutical company to set up a pharmaceutical factory in the People's Republic of China. [27] In 1976, Paul Janssen met Ma Haide (born George Shafik Hatem), a Lebanese-American doctor who had started working in China in 1933. After three days of meetings, the two agreed to bring a modernized ...
The Federal Court of Appeals in Canada ratified a Ministry of Health decision to refuse to provide Janssen Pharmaceuticals, a subsidiary of Johnson and Johnson (NYSE: JNJ), data protection for ...
An enantiomer of ketamine – esketamine commercially sold as Spravato – was approved as an antidepressant by the European Medicines Agency in 2019. [63] Esketamine was approved as a nasal spray for treatment-resistant depression in the United States [64] and elsewhere in 2019 (see Esketamine and Depression). The Canadian Network for Mood and ...
The personal information was part of a database used on the Janssen CarePath platform, according to IBM. IBM, which manages the database, said it was unable to determine the extent of the ...
Atypical antipsychotics include: Amisulpride (Solian) – approved in low doses as a monotherapy for persistent depression. Lumateperone (Caplyta) – approved as a monotherapy for bipolar depression. Lurasidone (Latuda) – approved as a monotherapy for bipolar depression. Quetiapine (Seroquel) – approved as a monotherapy for bipolar depression.
Pharmacology of antidepressants. The pharmacology of antidepressants is not entirely clear. The earliest and probably most widely accepted scientific theory of antidepressant action is the monoamine hypothesis (which can be traced back to the 1950s), which states that depression is due to an imbalance (most often a deficiency) of the monoamine ...
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