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2. Biden administration says Medicare negotiated price discounts ...

   www.aol.com/news/biden-administration-says...

   The list price of Merck's diabetes drug Januvia will be slashed to $113 for a 30-day supply from $527 as of 2023. Eliquis, a blood thinner from Bristol Myers Squibb and Pfizer, will cost $231 for ...

3. Apixaban - Wikipedia

   en.wikipedia.org/wiki/Apixaban

   Apixaban. Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa. [ 6][ 7][ 8] It is used an alternative to warfarin to prevent blood clots following hip or knee replacement and in ...

4. First-Time Negotiations Have Lowered Prices On 10 Expensive ...

   www.aol.com/biden-announce-drug-price-agreements...

   August 15, 2024 at 9:25 AM. The first-ever negotiations between the federal government and pharmaceutical companies have led to agreements that will lower the prices of 10 treatments, reducing ...

5. Which 10 prescription drug prices are dropping in 2026 after ...

   www.aol.com/10-prescription-drug-prices-dropping...

   Stelara. Stelara by Janssen Biotech, Inc. is used to treat psoriasis, psoriatic arthritis, Crohn’s disease and ulcerative colitis. The 2026 list price will drop 66% from $13,836 for a 30-day ...

6. Discovery and development of direct Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   The second one was apixaban (Eliquis), approved in Europe in 2011 and in the United States in 2012. The third one edoxaban (Lixiana, Savaysa) was approved in Japan in 2011 and in Europe and the US in 2015. Betrixaban (Bevyxxa) was approved in the US in 2017.

7. Rivaroxaban - Wikipedia

   en.wikipedia.org/wiki/Rivaroxaban

   Rivaroxaban inhibits both free and bound Factor Xa in the prothrombinase complex. [33] It is a selective direct factor Xa inhibitor with an onset of action of 2.5 to 4 hours. [ 34 ] Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade , inhibiting both thrombin formation and development of thrombi.

8. Medicare announces lower prices on 10 common, high-cost drugs

   www.aol.com/news/first-time-medicare-cuts-prices...

   Here are the negotiated prices for the drugs, based on a 30-day supply: Eliquis, a blood thinner from Bristol Myers Squibb and Pfizer: $231 negotiated price, down from $521 list price. Xarelto, a ...

9. List of largest selling pharmaceutical products - Wikipedia

   en.wikipedia.org/wiki/List_of_largest_selling...

   Trade name Type Main indications Company Sales (USD millions/year) ∆ vs 2014 1 Adalimumab: Humira Biologic Rheumatoid arthritis: AbbVie Inc. 14,012 1,469 2 Ledipasvir/sofosbuvir: Harvoni Small molecule Hepatitis C: Gilead Sciences: 13,864 11,737 3 Etanercept: Enbrel Biologic Rheumatoid arthritis: Amgen. Pfizer. 8,697 4,009 4 Infliximab ...