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Amitriptyline. Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches. [ 12] Due to the frequency and prominence of side effects, amitriptyline is ...
Nortriptyline is an active metabolite of amitriptyline by demethylation in the liver. Chemically, it is a secondary amine dibenzocycloheptene and pharmacologically it is classed as a first-generation antidepressant. [34] Nortriptyline may also have a sleep-improving effect due to antagonism of the H 1 and 5-HT 2A receptors. [35]
Tricyclic antidepressants ( TCAs) are a class of medications that are used primarily as antidepressants. TCAs were discovered in the early 1950s and were marketed later in the decade. [ 1] They are named after their chemical structure, which contains three rings of atoms. Tetracyclic antidepressants (TeCAs), which contain four rings of atoms ...
Give kiwi and prunes a try. There's research to suggest that two fruits in particular — kiwi and prunes — contain compounds that alleviate constipation, Gupta says. They don't even have to be ...
Dr. Rao recommends adding fermented foods such as kimchi, miso and kombucha to your diet. Some studies have shown that the p robiotic benefits of these foods can help with gastrointestinal issues ...
A clinical trial comparing its efficacy and tolerability with amitriptyline in the treatment of irritable bowel syndrome showed that tianeptine was at least as effective as amitriptyline and produced fewer prominent adverse effects, such as dry mouth and constipation. [27] Tianeptine has been reported to be very effective for asthma.
Discontinuation of treatment due to side effects was common. [ 64] Antidepressants including amitriptyline, fluoxetine, duloxetine, milnacipran, moclobemide, and pirlindole are recommended by the European League Against Rheumatism (EULAR) for the treatment of fibromyalgia based on "limited evidence".
Addressing the problem may require a multipronged approach since constipation, in general, is a multi-symptom problem, said Dr. William Chey, a professor of gastroenterology and nutritional ...
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