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The most common side effects are dry mouth, drowsiness, dizziness, constipation, and weight gain. Glaucoma , liver toxicity and abnormal heart rhythms are rare but serious side effects. Blood levels of amitriptyline vary significantly from one person to another, [ 17 ] and amitriptyline interacts with many other medications potentially ...
Amitriptyline (Elavil) Doxepin (Silenor) ... A study by JAMA Psychiatry found that amitriptyline is one of the depression medications most commonly linked to weight gain. Due to its side effects ...
Possibly also partly responsible for their weight gain liability. M 1: 12.9: 40: 1500: This is the main receptor responsible for the anticholinergic side effects mentioned above. M 3: 25.9: 50: 1848: This receptor is believed to be partly responsible for the metabolic adverse effects of the atypical antipsychotics. σ: 300: 2000: 31.5
Protriptyline. Protriptyline, sold under the brand name Vivactil among others, is a tricyclic antidepressant (TCA), specifically a secondary amine, indicated for the treatment of depression and attention-deficit hyperactivity disorder (ADHD). Uniquely among most of the TCAs, protriptyline tends to be energizing instead of sedating, and is ...
In Wikidata. Selective serotonin reuptake inhibitors ( SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into ...
Discontinuation of treatment due to side effects was common. [ 64] Antidepressants including amitriptyline, fluoxetine, duloxetine, milnacipran, moclobemide, and pirlindole are recommended by the European League Against Rheumatism (EULAR) for the treatment of fibromyalgia based on "limited evidence".
The 5-HT 2C receptors are one of three subtypes that belong to the serotonin 5-HT 2 receptor subfamily along with 5-HT 2A and 5-HT 2B receptors. The development of 5-HT 2C agonists has been a major obstacle, because of severe side effects due to a lack of selectivity over 5-HT 2A and 5-HT 2B receptors.
One study of SSRI side effects in 100 people found that 49% gained weight on Zoloft and 37.5% gained weight on Prozac (while 41% gained weight on Lexapro). How to avoid gaining weight on an ...