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  2. Tramadol - Wikipedia

    en.wikipedia.org/wiki/Tramadol

    Tramadol, sold under the brand name Ultram among others, [1] is an opioid pain medication and a serotonin–norepinephrine reuptake inhibitor (SNRI) used to treat moderately severe pain. [3][14] When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour. [3] It is also available by injection. [15] It is available in combination with ...

  3. List of side effects of tramadol - Wikipedia

    en.wikipedia.org/wiki/List_of_side_effects_of...

    Stomatitis (mouth swelling) Liver failure. Pulmonary oedema (fluid in the lungs) Gastrointestinal bleeding. Pulmonary embolism. Myocardial ischaemia (lack of blood supply to the heart muscles) Speech disorders. Haemoglobin decrease.

  4. Tramadol/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Tramadol/paracetamol

    D09999. Tramadol/paracetamol, also known as tramadol/acetaminophen and sold under the brand name Ultracet among others, is a fixed-dose combination medication used for the treatment of moderate to severe pain. [3][4] It contains tramadol, as the hydrochloride, an analgesic; and paracetamol an analgesic. [3][4] It is taken by mouth. [3][4]

  5. Desmetramadol - Wikipedia

    en.wikipedia.org/wiki/Desmetramadol

    Desmetramadol (INN), also known as O-desmethyltramadol (O-DSMT), is an opioid analgesic and the main active metabolite of tramadol. [2] Tramadol is demethylated by the liver enzyme CYP2D6 [3] to desmetramadol in the same way as codeine, and so similarly to the variation in effects seen with codeine, individuals who have a less active form of ...

  6. Medco Health Solutions - Wikipedia

    en.wikipedia.org/wiki/Medco_Health_Solutions

    Medco Health Solutions, Inc. was an American Pharmacy Benefits Management (PBM) company. Medco provided pharmacy services to private and public employers, health plans, labor unions, government agencies, and individuals served by Medicare Part D Prescription Drug Plans.

  7. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    Nonsteroidal anti-inflammatory drug. Non-steroidal anti-inflammatory drugs[1][3] (NSAID) [1] are members of a therapeutic drug class which reduces pain, [4] decreases inflammation, decreases fever, [1] and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of ...

  8. μ-opioid receptor - Wikipedia

    en.wikipedia.org/wiki/Μ-opioid_receptor

    Tramadol and tapentadol carry additional risks associated with their dual effects as SNRIs and can cause serotonin syndrome and seizures. Despite these risks, there is evidence to suggest that these drugs have a lower risk of respiratory depression compared to morphine.

  9. Codeine - Wikipedia

    en.wikipedia.org/wiki/Codeine

    Codeine is marketed as both a single-ingredient drug and in combination preparations with paracetamol (as co-codamol: e.g., brands Paracod, Panadeine, and the Tylenol-with-codeine series, including Tylenol 3 and 1, 2, and 4); with aspirin (as co-codaprin); or with ibuprofen (as Nurofen Plus). These combinations provide greater pain relief than ...