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The days of broad approvals for PD-1 inhibitors in stomach and esophageal cancers appear to be numbered. A group of external advisers to the FDA voted 10-2 that the use of PD-1 inhibitors in first-line, HER2-negative gastric cancer is not favorable in patients who have PD-L1-negative tumors, as measured by a combined positive score (CPS) or tumor area positivity (TAP) score below 1.
Anonymous board for AstraZeneca. ... AstraZeneca
AstraZeneca, Bristol-Myers submit US and EU application for Onglyza Trading Markets 7/23/08. Glaxo fails to hook investors Guardian, UK 7/23/08. Merck KGaA Net Falls Short on Crystals; Shares Drop Bloomberg 7/23/08
AstraZeneca’s Truqap flops in phase III triple-negative breast cancer trial Merck's Keytruda snags 40th US indication, leaps ahead of GSK with broad endometrial cancer approval Roche partners with RNA editing biotech Ascidian Merck gets shot in the arm with FDA approval for first pneumococcal vaccine designed for adults