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Phentermine (phenyl-tertiary-butyl amine), sold under the brand name Ionamin among others, is a medication used together with diet and exercise to treat obesity. [3] It is taken by mouth for up to a few weeks at a time, after which the benefits subside. [ 3 ]
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
e. Orlistat (Xenical), the most commonly used medication to treat obesity and sibutramine (Meridia), a medication that was withdrawn due to cardiovascular side effects. Anti-obesity medication or weight loss medications are pharmacological agents that reduce or control excess body fat. These medications alter one of the fundamental processes of ...
In 1984, researchers at the University of Rochester Medical Center reported that they had performed a double-blind, controlled clinical trial comparing phentermine alone, fenfluramine alone, a combination of phentermine and fenfluramine, and placebo, for weight loss in humans. Weight loss in those receiving the fen-phen combination was ...
Tesofensine ( NS2330) is a serotonin–noradrenaline–dopamine reuptake inhibitor from the phenyltropane family of drugs, which is being developed for the treatment of obesity. [ 1] Tesofensine was originally developed by a Danish biotechnology company, NeuroSearch, who transferred the rights to Saniona in 2014. [ 2]
Fenfluramine is a substituted amphetamine and is also known as 3-trifluoromethyl- N -ethylamphetamine. [ 8] It is a racemic mixture of two enantiomers, dexfenfluramine and levofenfluramine. [ 8] Some analogues of fenfluramine include norfenfluramine, benfluorex, flucetorex, and fludorex .
Phendimetrazine can essentially be thought of as an extended-release formulation of phenmetrazine with less potential for abuse. Phendimetrazine is an anorectic drug which acts as a norepinephrine - dopamine releasing agent (NDRA). [ 3] As an amphetamine congener, its structure incorporates the backbone of methamphetamine, a potent CNS stimulant.
(Reuters) -Archer Aviation on Thursday announced an agreement-in-principle with Stellantis under which the automaker would bear up to $370 million of labor-related costs to support a planned ramp ...
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