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Metastatic breast cancer. Metastatic breast cancer, also referred to as metastases, advanced breast cancer, secondary tumors, secondaries or stage IV breast cancer, is a stage of breast cancer where the breast cancer cells have spread to distant sites beyond the axillary lymph nodes. There is no cure for metastatic breast cancer; [1] there is ...
Breast cancer classification divides breast cancer into categories according to different schemes criteria and serving a different purpose. The major categories are the histopathological type, the grade of the tumor, the stage of the tumor, and the expression of proteins and genes. As knowledge of cancer cell biology develops these ...
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; [1] the term is typically used when referring to metastasis by a cancerous tumor. [2] The newly pathological sites, then, are metastases ( mets ). [3] [4] It is generally distinguished from cancer invasion, which is ...
Breast cancer is a cancer that develops from breast tissue. [7] Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. [1] In those with distant spread of the disease, there may be bone pain ...
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [2] [7] These contrast with benign tumors, which do not spread. [7] Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. [1]
Determining the extent to which a cancer has developed. Cancer staging is the process of determining the extent to which a cancer has grown and spread. A number from I to IV is assigned, with I being an isolated cancer and IV being a cancer that has metastasized and spread from its origin. The stage generally takes into account the size of a ...
Shannen Doherty revealed her stage 4 breast cancer has spread to her bones. This update comes almost six months after she told fans the cancer metastasized to her brain. “I’m not done with living.
Inflammatory breast cancer is a high-grade aneuploid cancer, with mutations and overexpression of p53, [13] high levels of E-cadherin and abnormal cadherin function. It is often regarded as a systemic cancer. A large number of IBC cases present as triple negative breast cancer (TNBC).
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