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Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body. [ 1][ 7][ 2] One nanogram per millilitre ( 1 ng/mL) is equivalent to 2.5 nanomoles per litre ( 2.5 nmol/L ). Severe deficiency: < 12 ng/mL = < 30 nmol/L[ 2 ...
Cholecalciferol is a form of vitamin D which is naturally synthesized in skin and functions as a pro-hormone, being converted to calcitriol. This is important for maintaining calcium levels and promoting bone health and development. [ 4] As a medication, cholecalciferol may be taken as a dietary supplement to prevent or to treat vitamin D ...
003468. LOINC. 24322-0, 24323-8. The comprehensive metabolic panel, or chemical screen ( CMP; CPT code 80053), is a panel of 14 blood tests that serves as an initial broad medical screening tool. The CMP provides a rough check of kidney function, liver function, diabetic and parathyroid status, and electrolyte and fluid balance, but this type ...
Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and for many other biological effects. [ 1][ 2] In humans, the most important compounds in this group are vitamin D 3 ( cholecalciferol) and vitamin D 2 ( ergocalciferol ). [ 2][ 3] The major natural source of ...
Calcitriol was identified as the active form of vitamin D in 1971 and the drug was approved for medical use in the United States in 1978. [7] It is available as a generic medication . [ 12 ] In 2021, it was the 258th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
Vitamin D-binding protein. Vitamin D-binding protein (DBP), also/originally known as gc-globulin ( g roup-specific c omponent), is a protein that in humans is encoded by the GC gene. [5] [6] DBP is genetically the oldest member of the albuminoid family and appeared early in the evolution of vertebrates. [7]
X-linked hypophosphatemia ( XLH) is an X-linked dominant form of rickets (or osteomalacia) that differs from most cases of dietary deficiency rickets in that vitamin D supplementation does not cure it. It can cause bone deformity including short stature and genu varum (bow-leggedness). It is associated with a mutation in the PHEX gene sequence ...
Vitamin D toxicity, or hypervitaminosis D, is the toxic state of an excess of vitamin D. The normal range for blood concentration in adults is 40 to 100 nanograms per milliliter (ng/mL). The normal range for blood concentration in adults is 40 to 100 nanograms per milliliter (ng/mL).
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