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Δ-8-tetrahydrocannabinol (delta-8-THC, [a] Δ 8-THC) is a psychoactive cannabinoid found in the Cannabis plant. [ 1 ] [ 2 ] [ 3 ] It is an isomer of delta-9-tetrahydrocannabinol (delta-9-THC, Δ 9 -THC), the compound commonly known as THC, with which it co-occurs in hemp ; natural quantities of ∆ 8 -THC found in hemp are low.
A cannabis edible, also known as a cannabis-infused food or simply an edible, is a food item (either homemade or produced commercially) that contains decarboxylated cannabinoids (cannabinoid acids converted to their orally bioactive form) from cannabis extract as an active ingredient. [1] Although edible may refer to either a food or a drink, a ...
Somatic effects. Bloodshot eye. Some of the short-term physical effects of cannabis use include increased heart rate, dry mouth, reddening of the eyes (congestion of the conjunctival blood vessels ), a reduction in intra-ocular pressure, muscle relaxation, and a sensation of cold or hot hands and feet. [53]
From January 1, 2021, to December 31, 2023, the FDA received over 300 adverse event reports involving children and adults who consumed delta-8 THC products, prompting the agency to issue a warning ...
In the United States, the use of cannabis for medical purposes is legal in 38 states, four out of five permanently inhabited U.S. territories, and the District of Columbia, as of March 2023. [1] Ten other states have more restrictive laws limiting THC content, for the purpose of allowing access to products that are rich in cannabidiol (CBD), a ...
Other concerns include difficulties for drug testing due to novel metabolites, or high potency/binding affinity of isomers for cannabinoid receptors showing potential for abuse (i.e., THCP, which has 33× the binding affinity of Δ 9-THC) [70] [71] From 2021 to 2023, the Δ 8-THC market generated US$2 billion in revenue. [72]
Tetrahydrocannabivarin ( THCV, THV, O-4394, GWP42004) is a homologue of tetrahydrocannabinol (THC) having a propyl (3-carbon) side chain instead of pentyl (5-carbon), making it non- psychoactive in lower doses. It has been shown to exhibit neuroprotective activity, appetite suppression, glycemic control and reduced side effects compared to THC ...
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