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Mackall has pioneered cancer immunotherapies for children. Her early research defined the effects of traditional cancer therapies on the immune system, where she identified the role of the thymus in human T cell regeneration and discovered that Interleukin-7 (IL-7) is the main regulator of T cell homeostasis in humans.
The Stanford prison experiment (SPE) was a psychological experiment conducted in August 1971. It was a two-week simulation of a prison environment that examined the effects of situational variables on participants' reactions and behaviors. Stanford University psychology professor Philip Zimbardo led the research team who administered the study. [1]
One of the earliest models for ethical human experimentation, preceding the Nuremberg Code, was established in 1931. [4] In the Weimar Republic of 20th century pre-Nazi Germany, the entity known as Reichsgesundheitsamt [5] (translating roughly to National Health Service), under the Ministry of the Interior [6] formulated a list of 14 points detailing these ethical principles.
The Glasgow Clinical Research Facility's former site at the Western Infirmary. The Glasgow Clinical Research Facility (Glasgow CRF) is a research centre at the Queen Elizabeth University Hospital in Govan, Glasgow, Scotland. History. Created on the 1 April 2006 from the NHS Clinical Research Grant Agreement with the CSO.
Clinical monitoring is the oversight and administrative efforts that monitor a participant's health and efficacy of the treatment during a clinical trial.Both independent and government-run grant-funding agencies, such as the National Institutes of Health (NIH) [1] and the World Health Organization (WHO), [2] require data and safety monitoring protocols for Phase I and II clinical trials ...
Clinical trials in the US are registered on clinicaltrials.gov. Clinicaltrials.gov is the largest clinical trials registry. Clinical trials conducted in the United States are required to be registered in the registry. Its registrations represent about 75% of what is available through the WHO portal (ICTRP).
During the 2019–20 academic year, Kunz was appointed a faculty research fellow at Stanford's Michelle R. Clayman Institute for Gender Research. Through this fellowship, she examined gender representation in her field including the disparities of women in clinical trials and leadership roles.
In drug development, preclinical development (also termed preclinical studies or nonclinical studies) is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals.